The sequence gamma-(312-324) is a fibrin-specific epitope
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The Sequence y - ( 312 - 324 ) Is a Fibrin - Specific Epitope
Fibrin accelerates the activation of plasminogen catalyzed by tissue-type plasminogen activator much stronger than fibrinogen. Detailed studies showed that (part of) this rateenhacing effect of fibrin is brought about by two sites in the fibrin molecule: one in Aa-(148-160) and one in the rchain stretch 31 1-379 (also known as FCB-5). During the fibrinogento-fibrin conversion, Aa-( 148-160) app...
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ژورنال
عنوان ژورنال: Blood
سال: 1991
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v77.10.2169.2169